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Translational Medicine / 转化医学Hereditary Pancreatic Cancer Surveillance, High-Risk Programs

Randall Brand

MD

🏢University of Pittsburgh🌐USA

Professor of Medicine and Director, GI Cancer Risk and Prevention

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👥Biography 个人简介

Randall Brand leads research on pancreatic cancer surveillance in hereditary high-risk populations. His research developed and validated surveillance protocols using MRI/MRCP and endoscopic ultrasound to detect early-stage pancreatic cancer and high-risk precursor lesions in patients with BRCA1/2, PALB2, ATM, and other germline variants associated with pancreatic cancer risk. He has contributed to the Cancer of the Pancreas Screening (CAPS) consortium evidence base for pancreatic cancer surveillance recommendations in high-risk individuals. His work demonstrates that surveillance in hereditary high-risk patients can detect early-stage resectable pancreatic cancer with improved survival outcomes.

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🧪Research Fields 研究领域

hereditary pancreatic cancer
BRCA2 PDAC risk
PDAC surveillance MRI EUS
high-risk pancreas program
genetic predisposition PDAC

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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