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Translational Medicine / 转化医学Cancer Biomarker & Pathology

Rajendra Singh

拉金德拉·辛格

MD

🏢NYU Langone Health(纽约大学朗格尼健康中心)🌐USA

Professor of Pathology, Director of Endocrine Pathology病理学教授,内分泌病理学主任

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h-index
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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Expert in thyroid and endocrine cancer pathology with focus on molecular diagnostics. Developed and validated BRAF V600E immunohistochemistry as a rapid screening tool for papillary thyroid carcinoma, influencing preoperative diagnostic algorithms and surgical planning.

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🧪Research Fields 研究领域

Thyroid Cancer Molecular Diagnostics甲状腺癌分子诊断
BRAF IHC BiomarkersBRAF免疫组化生物标志物
Endocrine Pathology内分泌病理学

🎓Key Contributions 主要贡献

BRAF V600E IHC Validation

Conducted landmark validation studies of the VE1 antibody clone for BRAF V600E detection in thyroid fine needle aspirates and core biopsies, enabling rapid intraoperative and preoperative molecular diagnosis.

Thyroid FNA Molecular Integration

Developed integrated cytopathology-molecular testing algorithms for indeterminate thyroid nodules, combining IHC markers with next-generation sequencing to reduce unnecessary thyroidectomies.

Representative Works 代表性著作

[1]

BRAF V600E Immunohistochemistry in Thyroid Fine-Needle Aspiration: Accuracy and Impact on Clinical Management

Thyroid (2023)

Demonstrated VE1 IHC sensitivity of 97% and specificity of 99% for BRAF V600E in thyroid FNA specimens, supporting routine clinical adoption.

[2]

Integrated Molecular and Histopathologic Profiling of Poorly Differentiated Thyroid Carcinoma

Modern Pathology (2022)

Characterized molecular landscape of poorly differentiated thyroid carcinoma with actionable alterations in 72% of cases.

🏆Awards & Recognition 奖项与荣誉

🏆American Thyroid Association Research Achievement Award
🏆NYU Langone Pathology Excellence Award
🏆United States and Canadian Academy of Pathology Young Investigator Award

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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