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Translational Medicine / 转化医学mRNA vs Peptide Cancer Vaccine Comparison

Priya Bhatt

MD, PhD

🏢Fred Hutchinson Cancer Center🌐USA

Associate Professor of Vaccine Biology

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👥Biography 个人简介

Priya Bhatt conducts head-to-head translational studies comparing mRNA and peptide-based cancer vaccine platforms for neoantigen immunogenicity and clinical efficacy. Her research has demonstrated that mRNA vaccines can induce more potent and broader CD8+ and CD4+ T cell responses compared to synthetic long peptide vaccines due to efficient antigen presentation. She has characterized how LNP-mRNA vaccines engage dendritic cell cross-presentation pathways critical for CD8+ CTL induction. Her comparative studies inform platform selection for next-generation personalized cancer vaccines.

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🧪Research Fields 研究领域

mRNA vaccine immunogenicity
peptide vaccine
vaccine platform comparison
T cell responses
neoantigen vaccine

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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