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Translational Medicine / 转化医学Myeloproliferative Neoplasms, Pacritinib

Prithviraj Bose

MD

🏢University of Texas MD Anderson Cancer Center🌐USA

Associate Professor, Department of Leukemia

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👥Biography 个人简介

Prithviraj Bose is a clinical investigator specializing in myeloproliferative neoplasms with particular expertise in JAK inhibitor therapy for myelofibrosis. He led and contributed to pivotal PERSIST trials evaluating pacritinib for patients with myelofibrosis and severe thrombocytopenia, a population in whom ruxolitinib is often contraindicated. His research characterizes mechanisms of resistance to JAK inhibitors and evaluates rational combination partners including navitoclax. He is an active educator and mentor in the myeloid malignancies field.

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🧪Research Fields 研究领域

pacritinib myelofibrosis
JAK2/IRAK1 inhibition
thrombocytopenic myelofibrosis
PERSIST trials
myelofibrosis low platelet count

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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