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Translational Medicine / 转化医学Leptomeningeal Disease CNS

Priscilla Brastianos

MD

🏢Massachusetts General Hospital Cancer Center🌐USA

Director of Central Nervous System Metastasis Program

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👥Biography 个人简介

Priscilla Brastianos leads trials of intrathecal therapies including trastuzumab and novel agents for leptomeningeal disease from breast and lung cancer. Her translational work characterizes CNS metastasis biology through CSF ctDNA and genomic profiling of brain metastases. She has transformed precision oncology for CNS involvement across tumor types.

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🧪Research Fields 研究领域

leptomeningeal disease intrathecal therapy
CNS metastasis precision oncology
CSF ctDNA
intrathecal trastuzumab
CNS tropism biology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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