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Translational Medicine / 转化医学Tumor Microenvironment, Lactate Shuttle
Pierre Sonveaux
PhD
🏢UCLouvain🌐Belgium
Professor of Pharmacology
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Key Papers
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Key Contributions
👥Biography 个人简介
Pierre Sonveaux established the lactate shuttle hypothesis in tumors whereby oxidative cancer cells consume lactate produced by glycolytic cells via MCT1. This work reframed lactate as a fuel and therapeutic target, linking pH regulation with tumor metabolic cooperativity.
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🧪Research Fields 研究领域
MCT1 lactate transporter
lactate fuel symbiosis
oxidative cancer cell fueling
metabolic heterogeneity
pH lactate crosstalk
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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