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Translational Medicine / 转化医学FLASH Brain Sparing, Neuroprotection

Pierre Montay-Gruel

PhD

🏢University of California, Irvine🌐USA

Assistant Professor of Radiation Oncology

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Key Contributions

👥Biography 个人简介

Pierre Montay-Gruel demonstrated the remarkable neuroprotective effects of FLASH radiotherapy, showing that FLASH whole-brain irradiation preserves cognitive function and hippocampal neurogenesis that are destroyed by conventional dose-rate radiation. His preclinical studies in mouse models provided compelling evidence that FLASH can deliver therapeutic brain doses while avoiding radiation-induced cognitive decline, a major concern in brain cancer and prophylactic cranial irradiation.

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🧪Research Fields 研究领域

FLASH brain sparing
cognitive preservation radiation
FLASH neuroprotection
whole brain FLASH RT
hippocampal protection

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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