Pierre Bhatt

Pierre Bhatt investigates the stromal vascular compartment of tumors, particularly how tumor-associated pericytes and endothelial cells contribute to the immunosuppressive microenvironment. His research has explored the concept of vascular normalization as a strategy to improve drug and immune cell access to tumors. He has characterized how abnormal tumor vasculature contributes to hypoxia, metabolic reprogramming, and immune exclusion. His work on pericyte biology has identified potential combinatorial strategies involving anti-angiogenic agents with immunotherapy.