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Translational Medicine / 转化医学T-Cell Lymphoma, ALCL Biology

Pier Giuseppe Pelicci

MD, PhD

🏢IEO - European Institute of Oncology🌐Italy

Director, Department of Experimental Oncology

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Key Contributions

👥Biography 个人简介

Pier Giuseppe Pelicci made landmark contributions to understanding the molecular biology of ALK-positive anaplastic large cell lymphoma, including characterizing the oncogenic properties of the NPM-ALK fusion protein arising from t(2;5) translocation. His translational work revealed how NPM-ALK drives cell proliferation and survival through multiple downstream pathways, informing the development of ALK inhibitors in ALCL. He is a pioneer in cancer molecular oncology.

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🧪Research Fields 研究领域

ALK-positive ALCL
NPM-ALK oncogene
ALCL pathobiology
anaplastic large cell lymphoma genetics
tyrosine kinase lymphoma

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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