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Translational Medicine / 转化医学DLBCL Bispecific Antibodies, Glofitamab

Philip Savage

MD

🏢BC Cancer Agency, University of British Columbia🌐Canada

Clinical Professor, Division of Medical Oncology

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👥Biography 个人简介

Philip Savage is a lymphoma oncologist specializing in relapsed/refractory DLBCL and the development of CD20xCD3 bispecific T cell engagers. He contributed to the pivotal glofitamab trial in relapsed/refractory DLBCL demonstrating durable complete responses leading to FDA approval in 2023. His research addresses sequencing of bispecific antibodies and CAR-T in DLBCL, management of cytokine release syndrome, and emerging resistance mechanisms. He participates in NCI-Canada and ALLIANCE lymphoma studies and contributes to Canadian consensus guidelines for DLBCL management.

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🧪Research Fields 研究领域

glofitamab bispecific antibody DLBCL
mosunetuzumab DLBCL follicular
CD20 CD3 bispecific antibodies
DLBCL relapsed refractory third-line bispecific
cytokine release syndrome bispecific management

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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