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Translational Medicine / 转化医学SCLC Molecular Resistance, Neuroendocrine Differentiation

Petros Christopoulos

MD, PhD

🏢Heidelberg University Hospital / Thoraxklinik🌐Germany

Head of the Clinical Research Unit, Thoracic Oncology

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👥Biography 个人简介

Petros Christopoulos is a translational thoracic oncologist focused on the molecular mechanisms of SCLC progression, neuroendocrine differentiation, and therapy resistance. His research has addressed circulating tumor cell analysis in SCLC, plasticity between SCLC molecular subtypes, and predictive genomic biomarkers for response to novel agents including tarlatamab. He participates in European SCLC trial networks and investigates rare SCLC features including transformation from NSCLC. His work advances understanding of SCLC biology and how molecular subtyping can guide future therapeutic development.

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🧪Research Fields 研究领域

SCLC plasticity neuroendocrine transdifferentiation
SCLC treatment resistance molecular
SCLC chemotherapy response prediction
tarlatamab DLL3 bispecific antibody
SCLC next-generation sequencing Germany

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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