Peter van den Elsen
PhD
Professor of Transplantation Immunology
👥Biography 个人简介
Peter van den Elsen has made important contributions to understanding the transcriptional and epigenetic regulation of MHC and antigen processing genes in cancer. His work revealed how cancer cells silence TAP1, TAP2, and tapasin through promoter methylation and histone deacetylation, disrupting the peptide loading complex. He has shown that epigenetic drugs can restore antigen processing machinery expression and improve immunotherapy response.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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