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Translational Medicine / 转化医学Nanotechnology, Antibody-Drug Conjugate Linkers

Peter Senter

PhD

🏢Seagen / Pfizer Oncology🌐USA

Senior Vice President

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Key Contributions

👥Biography 个人简介

Peter Senter developed the linker-drug technology underpinning the auristatin-based antibody-drug conjugate platform at Seattle Genetics. His work on maleimide linkers and the MMAE payload enabled development of brentuximab vedotin, enfortumab vedotin, and other FDA-approved ADCs. He has contributed to the chemistry of site-specific conjugation and cleavable linker design that enabled modern ADC precision oncology.

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🧪Research Fields 研究领域

antibody-drug conjugate linker chemistry
maleimide ADC linker design
auristatin MMAE ADC
Seattle Genetics ADC technology
site-specific ADC conjugation

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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