Peter Ratcliffe
MB BChir
Director of Clinical Research
👥Biography 个人简介
Peter Ratcliffe at the Crick Institute and Oxford shared the 2019 Nobel Prize for discovering the molecular mechanism of oxygen sensing, including demonstrating that prolyl hydroxylase domain (PHD) enzymes hydroxylate HIF-alpha under normoxia to enable VHL-mediated degradation. His foundational work on the oxygen sensing pathway has elucidated mechanisms driving cancer angiogenesis and hypoxic adaptation.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
Related Experts 相关专家
Antoni Ribas
UCLA Jonsson Comprehensive Cancer Center
Drew M. Pardoll
Johns Hopkins University
Padmanee Sharma
MD Anderson Cancer Center
Naiyer A. Rizvi
Columbia University Irving Medical Center
关注 Peter Ratcliffe 的研究动态
Follow Peter Ratcliffe's research updates
留下邮箱，当我们发布与 Peter Ratcliffe（Francis Crick Institute / Oxford）相关的新研究或访谈时，我们会通知你。
Explore More Experts
Discover the researchers shaping the future of cancer treatment