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Translational Medicine / 转化医学DNA Methylation Profiling, TCGA Epigenomics

Peter Laird

PhD

🏢Van Andel Institute🌐USA

Professor of Biochemistry and Molecular Medicine

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👥Biography 个人简介

Peter Laird is a leading authority on genome-wide DNA methylation profiling in cancer, having directed epigenomic analyses for The Cancer Genome Atlas (TCGA) consortium across dozens of tumor types. His laboratory defined CpG island methylator phenotypes across multiple cancers and developed computational methods for methylation-based molecular classification that have become standard in precision oncology. He has been instrumental in translating Illumina Infinium methylation array technology from research discovery to clinical diagnostic application, enabling methylation-based brain tumor classification systems now used worldwide.

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🧪Research Fields 研究领域

DNA methylation profiling TCGA
CpG island methylator phenotype CIMP
Illumina methylation array cancer
pan-cancer epigenomic classification
methylation-based tumor subtyping

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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