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Translational Medicine / 转化医学Wilms Tumor, Pediatric Kidney Cancer

Peter Grundy

MD

🏢University of Alberta🌐Canada

Professor Emeritus

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Key Contributions

👥Biography 个人简介

Peter Grundy has contributed to Wilms tumor (nephroblastoma) research — the most common kidney cancer in children — including cooperative group clinical trial contributions through the Children's Oncology Group (COG). Wilms tumor is one of the greatest successes of pediatric oncology, with 5-year survival over 90% for most patients, achieved through risk-adapted multimodality treatment. Research on WT1, WTX, and CTNNB1 mutations in Wilms tumor biology has contributed to molecular understanding.

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🧪Research Fields 研究领域

Wilms tumor nephroblastoma
WT1 tumor suppressor
pediatric kidney cancer biology
COG Wilms tumor trials
nephroblastoma genetics

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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