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Translational Medicine / 转化医学Brain Tumor Stem Cells, Glioblastoma

Peter Dirks

MD, PhD

🏢Hospital for Sick Children, University of Toronto🌐Canada

Professor and Head, Division of Neurosurgery

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👥Biography 个人简介

Peter Dirks identified cancer stem cells in brain tumors, demonstrating that CD133-positive cells from glioblastoma can initiate tumor growth upon transplantation. His laboratory has extensively characterized the glioblastoma stem cell population, showing its role in treatment resistance, tumor recurrence, and cellular heterogeneity. He integrates single-cell genomics and lineage tracing to understand brain cancer stem cell dynamics in patients. His work has opened new therapeutic avenues targeting the cells responsible for inevitable glioblastoma recurrence.

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🧪Research Fields 研究领域

brain tumor stem cells
glioblastoma
medulloblastoma
neural stem cells
tumor recurrence

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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