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Translational Medicine / 转化医学BiTE, Hematologic Malignancies

Peter Bhatt

MD, PhD

🏢Johns Hopkins Sidney Kimmel Comprehensive Cancer Center🌐USA

Director, T-Cell Engaging Therapeutics Program

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👥Biography 个人简介

Dr. Peter Bhatt is a hematologic oncologist and translational scientist specializing in T-cell engaging bispecific antibodies. His laboratory investigates mechanisms of blinatumomab resistance in B-cell acute lymphoblastic leukemia including CD19 downregulation, T-cell exhaustion, and immunosuppressive microenvironment factors. He leads early-phase trials evaluating novel BiTE formats and combination strategies to overcome blinatumomab resistance.

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🧪Research Fields 研究领域

blinatumomab BiTE mechanism
blinatumomab resistance
CD3 CD19 bispecific T-cell engager
B-ALL treatment blinatumomab
immune synapse BiTE

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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