Paulo Hoff
保罗·霍夫
MD, PhD
Director of Oncology肿瘤学主任
👥Biography 个人简介
Paulo Hoff is a leading GI oncologist and drug development expert at Hospital Sírio-Libanês in São Paulo. A co-founder and key force behind LACOG, he has advanced clinical trial infrastructure across Latin America and contributed to global colorectal and pancreatic cancer research.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
GI Oncology Drug Development
Led multiple phase II/III trials in colorectal and pancreatic cancer, establishing Brazil as a key site for global oncology drug development and expanding treatment access.
LACOG Network Building
Co-founded the Latin American Cooperative Oncology Group (LACOG), enabling large-scale, high-quality clinical research across Brazil and the broader Latin American region.
Translational Research
Pioneered translational studies linking molecular tumor profiling with clinical outcomes in GI cancers, improving patient selection for targeted therapies in Latin America.
Representative Works 代表性著作
Regorafenib plus modified FOLFOX6 as first-line treatment of metastatic colorectal cancer
ESMO Open (2021)
Phase II study demonstrating feasibility and early efficacy of regorafenib combined with chemotherapy in mCRC patients in Latin America.
Oncology in Latin America: challenges and opportunities
JCO Global Oncology (2020)
Comprehensive analysis of cancer care gaps and research opportunities across Latin America, shaping policy and funding priorities.
Clinical characteristics and outcomes of pancreatic cancer in Brazil
Pancreatology (2019)
First large Brazilian registry study characterizing pancreatic cancer epidemiology and treatment patterns in a middle-income country context.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
Related Experts 相关专家
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UCLA Jonsson Comprehensive Cancer Center
Drew M. Pardoll
Johns Hopkins University
Padmanee Sharma
MD Anderson Cancer Center
Naiyer A. Rizvi
Columbia University Irving Medical Center
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