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Translational Medicine / 转化医学Peritoneal Oncology & HIPEC

Paul H. Sugarbaker

保罗·苏加贝克

MD, FACS, FRCS

🏢MedStar Washington Hospital Center(美德星华盛顿医院中心)🌐USA

Director, Program in Peritoneal Surface Oncology腹膜表面肿瘤学项目主任

68
h-index
3
Key Papers
4
Awards
3
Key Contributions

👥Biography 个人简介

Paul H. Sugarbaker is the pioneering father of peritoneal surface oncology and HIPEC. Over five decades at MedStar Washington Hospital Center, he developed and standardized cytoreductive surgery (CRS) combined with HIPEC, transforming peritoneal metastases from universally fatal to potentially curable. He established the peritoneal cancer index (PCI) and completeness-of-cytoreduction score used worldwide.

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🧪Research Fields 研究领域

Peritoneal Surface Oncology腹膜表面肿瘤学
HIPEC腹腔热灌注化疗
Cytoreductive Surgery肿瘤减灭手术
Pseudomyxoma Peritonei腹膜假性黏液瘤
Peritoneal Mesothelioma腹膜间皮瘤
Appendiceal Neoplasms阑尾肿瘤

🎓Key Contributions 主要贡献

Cytoreductive Surgery and HIPEC Standardization

Developed and globally disseminated the combined CRS + HIPEC approach for peritoneal surface malignancies, including detailed surgical techniques, patient selection criteria, and the peritoneal cancer index (PCI) scoring system adopted worldwide.

Pseudomyxoma Peritonei Treatment

Established CRS + HIPEC as the curative-intent standard for pseudomyxoma peritonei and appendiceal mucinous neoplasms, reporting long-term survival outcomes at his Washington center over thousands of cases.

Peritoneal Mesothelioma Outcomes

Demonstrated that aggressive CRS + HIPEC in selected patients with malignant peritoneal mesothelioma achieves median survival exceeding 5 years, establishing surgical treatment as superior to systemic therapy alone.

Representative Works 代表性著作

[1]

Peritoneal Carcinomatosis: Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy

Seminars in Surgical Oncology (1996)

Landmark paper establishing the rationale and technique for CRS + HIPEC, becoming foundational reading for peritoneal oncology.

[2]

Long-term survival with cytoreductive surgery and perioperative intraperitoneal chemotherapy for peritoneal carcinomatosis

Annals of Surgery (2001)

Reported long-term survival data for CRS + HIPEC across multiple peritoneal malignancies, cementing the role of aggressive locoregional treatment.

[3]

Pseudomyxoma peritonei syndrome

Diseases of the Colon & Rectum (2002)

Comprehensive analysis of CRS + HIPEC outcomes in pseudomyxoma peritonei, establishing current treatment standards.

🏆Awards & Recognition 奖项与荣誉

🏆Pioneer Award, Peritoneal Surface Oncology Group International (PSOGI)
🏆Distinguished Service Award, Society of Surgical Oncology
🏆Honorary Fellowship, Royal College of Surgeons of England
🏆Lifetime Achievement Award, American Society of Peritoneal Surface Malignancies

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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