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Translational Medicine / 转化医学Merkel Cell Carcinoma

Paul Nghiem

MD, PhD

🏢University of Washington🌐USA

Professor and Head, Dermatology

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Key Contributions

👥Biography 个人简介

Paul Nghiem is the world's leading expert on Merkel cell carcinoma, a rare but aggressive neuroendocrine skin cancer, at the University of Washington. He has led pivotal immunotherapy trials including avelumab and pembrolizumab studies that transformed MCC treatment. His laboratory defined the role of Merkel cell polyomavirus in MCC pathogenesis and immune evasion. He established the MCC registry and maintains a global resource for research on this rare malignancy.

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🧪Research Fields 研究领域

Merkel cell carcinoma
avelumab MCC
pembrolizumab MCC
Merkel cell polyomavirus
neuroendocrine skin cancer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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