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Translational Medicine / 转化医学Albumin-Bound Nanoparticle, nab-Paclitaxel

Patrick Soon-Shiong

MB ChB MMed

🏢ImmunityBio🌐USA

Executive Chairman

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Key Contributions

👥Biography 个人简介

Patrick Soon-Shiong developed nab-paclitaxel (Abraxane) — a pioneering albumin-bound nanoparticle formulation of paclitaxel that improved tolerability and activity compared to cremophor-solubilized paclitaxel. Abraxane received FDA approval for breast cancer, NSCLC, and pancreatic cancer (in combination with gemcitabine), and represented one of the first nanomedicine oncology approvals to achieve widespread clinical use.

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🧪Research Fields 研究领域

nab-paclitaxel Abraxane
albumin-bound nanoparticle cancer
pancreatic cancer nab-paclitaxel gemcitabine
SPARC albumin nanoparticle
nanoparticle chemotherapy delivery

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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