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Translational Medicine / 转化医学Bispecific Antibodies, T Cell Engagers

Patrick Bhatt

MD

🏢City of Hope🌐USA

Hematologic Oncologist

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Key Papers
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Key Contributions

👥Biography 个人简介

Patrick Bhatt has contributed to clinical development and application of bispecific antibodies in hematologic malignancies. Bispecific T cell engagers (BiTEs) like blinatumomab redirect T cells to kill cancer cells by simultaneously binding CD19 on B cells and CD3 on T cells, achieving impressive response rates in relapsed/refractory B-ALL. Understanding optimal use, resistance mechanisms, and combination strategies for bispecific antibodies in lymphoma and leukemia addresses important clinical questions.

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🧪Research Fields 研究领域

bispecific antibody cancer
blinatumomab BiTE ALL
T cell engager cancer
CD19 CD3 bispecific
bispecific antibody hematologic cancer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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