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Translational Medicine / 转化医学HER2 TKI NSCLC

Pasi Janne

MD, PhD

🏢Dana-Farber Cancer Institute🌐USA

Professor of Medicine

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Key Contributions

👥Biography 个人简介

Pasi Janne has driven translational lung cancer drug development including HER2-selective tyrosine kinase inhibitors for HER2 exon 20 insertion NSCLC. His work characterizes HER2 kinase structure and resistance biology in lung cancer. He continues to lead early-phase trials of novel HER2-selective and broad-spectrum TKIs.

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🧪Research Fields 研究领域

HER2 TKI NSCLC
HER2 exon 20 biology
poziotinib DESTINY
HER2 kinase structure NSCLC
lung cancer drug development

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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