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Translational Medicine / 转化医学cfDNA Fragmentomics

Nicholas Papadopoulos

PhD

🏢Johns Hopkins University School of Medicine🌐USA

Professor of Oncology and Pathology

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Key Contributions

👥Biography 个人简介

Nicholas Papadopoulos co-developed CancerSEEK, a multi-analyte blood test combining cfDNA mutations with protein biomarkers for multi-cancer early detection, and has been instrumental in integrating fragmentomics features into next-generation liquid biopsy platforms. His work on combining genomic, fragmentomic, and proteomic features in a single assay has achieved unprecedented sensitivity for early-stage cancers. His leadership of large-scale prospective clinical trials has established the clinical validity of cfDNA-based multi-cancer screening in asymptomatic populations.

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🧪Research Fields 研究领域

CancerSEEK blood test
Multi-analyte cancer detection
cfDNA plus protein biomarkers
Early cancer detection
Liquid biopsy clinical trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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