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Translational Medicine / 转化医学Tumor Initiation, Colorectal Cancer Models
Owen Sansom
PhD
🏢CRUK Scotland Institute🌐UK
Director
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Key Papers
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Key Contributions
👥Biography 个人简介
Owen Sansom has dissected APC and Wnt pathway roles in intestinal tumor initiation using sophisticated mouse genetics. His work illuminated how loss of APC drives crypt hyperproliferation and adenoma formation. He directs the CRUK Scotland Institute in Glasgow.
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🧪Research Fields 研究领域
APC Wnt pathway
colorectal cancer models
cell of origin
mouse genetics
tumor initiation
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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