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Translational Medicine / 转化医学Diffuse Midline Glioma H3K27M

Oren Becher

MD

🏢Icahn School of Medicine at Mount Sinai🌐USA

Professor of Pediatrics

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Key Contributions

👥Biography 个人简介

Oren Becher leads translational and clinical research on diffuse intrinsic pontine glioma and H3K27M-altered diffuse midline glioma, contributing to trials of ONC201 (dordaviprone) and related agents. His work has defined molecular subsets of midline gliomas and accelerated DIPG drug development. He has shaped pediatric brainstem tumor treatment approaches.

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🧪Research Fields 研究领域

diffuse intrinsic pontine glioma
H3K27M midline glioma
ONC201 dordaviprone
pediatric brainstem tumor
DIPG clinical trials

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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