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Translational Medicine / 转化医学Cancer Trials, Dose Escalation Design
John O'Quigley
PhD
🏢Sorbonne Universite and University College London🌐United Kingdom
Professor of Biostatistics
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Key Papers
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Key Contributions
👥Biography 个人简介
John O'Quigley developed the Continual Reassessment Method (CRM) that transformed modern phase I oncology trial design. His work has provided rigorous statistical frameworks for adaptive dose escalation. He is widely regarded as a founding figure in model-based dose finding methodology.
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🧪Research Fields 研究领域
continual reassessment method
phase I design
adaptive trials
biostatistics
dose finding
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-04-01 | All information from publicly available academic sources
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