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Translational Medicine / 转化医学Lu-177 PSMA Radioligand Therapy, Prostate Cancer

Oliver Sartor

MD

🏢Tulane University School of Medicine🌐USA

Medical Director, Tulane Cancer Center

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Key Contributions

👥Biography 个人简介

Oliver Sartor has been a central figure in the clinical development of radioligand therapy for prostate cancer, serving as lead investigator for pivotal trials that established Lu-177 PSMA-617 (Pluvicto) and radium-223 as standard-of-care treatments. His work on the VISION trial demonstrated that Lu-177 PSMA-617 significantly extends overall survival and radiographic progression-free survival in PSMA-positive metastatic castration-resistant prostate cancer, leading to FDA approval. He has advanced the theranostic paradigm in which PSMA PET imaging selects patients for PSMA-targeted radioligand therapy. His clinical research on sequencing and combining radioligand therapies with androgen receptor pathway inhibitors and immunotherapy is defining optimal treatment strategies.

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🧪Research Fields 研究领域

Lu-177 PSMA-617 radioligand therapy prostate
VISION trial mCRPC Lu-177
theranostic paradigm prostate cancer
radium-223 bone metastasis prostate
radioligand therapy clinical development

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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