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Translational Medicine / 转化医学Myeloma Bispecifics, CAR-T, Novel Immunotherapy

Noopur Raje

MD

🏢Massachusetts General Hospital, Harvard Medical School🌐USA

Director, Center for Multiple Myeloma; Professor of Medicine

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👥Biography 个人简介

Noopur Raje is a myeloma specialist leading the MGH myeloma program who has been a principal investigator in pivotal trials of BCMA-directed CAR-T therapies and bispecific T-cell engagers. She participated in the KarMMa trial of idecabtagene vicleucel (ide-cel) and multiple bispecific antibody trials including teclistamab (MajesTEC-1) and elranatamab. Her research encompasses mechanisms of BCMA antigen loss and resistance to immunotherapy, and she investigates strategies for sequencing novel immunotherapy in heavily pre-treated myeloma. She also studies smoldering myeloma interception strategies.

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🧪Research Fields 研究领域

BCMA bispecific antibodies myeloma
ide-cel CAR-T myeloma
teclistamab elranatamab myeloma bispecific
myeloma T cell engager therapy
smoldering myeloma prevention MGH

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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