Nina Bhatt

Nina Bhatt focuses on pharmacogenomic variation in drug transporters that affect the cellular uptake and efflux of anticancer agents. Her research has characterized how genetic variants in ABCB1, ABCG2, and organic anion transporting polypeptides influence the pharmacokinetics and tissue distribution of chemotherapy drugs. She has identified transporter gene polymorphisms associated with altered efficacy and toxicity of methotrexate, anthracyclines, and platinum compounds. Her work illuminates how transporter pharmacogenomics complements enzyme pharmacogenomics in determining individual cancer drug responses.