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Translational Medicine / 转化医学Breast Cancer Genomics, ctDNA

Nikhil Wagle

MD

🏢Dana-Farber Cancer Institute🌐USA

Medical Oncologist

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Key Contributions

👥Biography 个人简介

Nikhil Wagle at Dana-Farber has pioneered studies of acquired endocrine therapy resistance in breast cancer through liquid biopsy, characterizing ESR1 mutations detectable in plasma as early markers of resistance to aromatase inhibitors. He leads the Count Me In project enabling direct patient participation in cancer genomics research, and has contributed to understanding of breast cancer evolutionary dynamics during treatment.

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🧪Research Fields 研究领域

breast cancer genomics
ctDNA
endocrine resistance
ESR1 mutations
liquid biopsy

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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