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Translational Medicine / 转化医学Teclistamab, BCMAxCD3 Myeloma

Niels van de Donk

MD, PhD

🏢Amsterdam University Medical Centers🌐Netherlands

Professor of Hematology

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Key Contributions

👥Biography 个人简介

Niels van de Donk at Amsterdam UMC is a leading multiple myeloma researcher who has contributed to the clinical development of teclistamab (BCMA x CD3) and other bispecific antibodies for relapsed/refractory myeloma. His participation in the MajesTEC-1 trial helped establish teclistamab as a novel treatment for heavily pre-treated patients. He has contributed to characterizing the immunological mechanisms and resistance patterns of BCMA-targeted bispecifics. His work spans plasma cell biology, novel drug development, and myeloma treatment optimization.

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🧪Research Fields 研究领域

teclistamab BCMAxCD3
MajesTEC trial
multiple myeloma bispecific
BCMA-targeting myeloma
myeloma T-cell redirection

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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