Nicoletta Colombo
尼科莱塔·科伦坡
MD, PhD
Director, Gynecology Program; Professor of Gynecologic Oncology, University of Milan-Bicocca妇科项目主任；米兰比可卡大学妇科肿瘤学教授
👥Biography 个人简介
Nicoletta Colombo is Director of the Gynecology Program at the European Institute of Oncology (IEO), Milan, and a leading authority in gynecologic oncology globally. She was principal investigator of the GARNET trial establishing dostarlimab for mismatch repair-deficient recurrent endometrial cancer, and has contributed to pivotal trials in ovarian cancer including PARP inhibitor maintenance and immunotherapy combinations. She chairs ESMO gynecologic oncology guidelines.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
GARNET Trial: Dostarlimab in MMRd Endometrial Cancer
PI of the GARNET phase I trial demonstrating durable responses to dostarlimab (anti-PD-1) in mismatch repair-deficient recurrent or advanced endometrial cancer, leading to FDA approval and establishing immunotherapy as standard salvage for MMRd gynecologic cancers.
ESMO Gynecologic Oncology Clinical Practice Guidelines
Chairs and co-authors ESMO Clinical Practice Guidelines for endometrial and ovarian cancer, synthesizing global trial evidence into international treatment recommendations adopted by oncologists worldwide.
Representative Works 代表性著作
Dostarlimab for Recurrent Endometrial Cancer (GARNET)
Journal of Clinical Oncology (2021)
Phase I GARNET trial demonstrating durable antitumor activity of dostarlimab in MMR-deficient recurrent endometrial cancer, supporting regulatory approval.
ESMO Clinical Practice Guidelines: Newly Diagnosed and Relapsed Epithelial Ovarian Cancer
Annals of Oncology (2023)
Comprehensive ESMO guidelines synthesizing evidence on first-line and recurrence treatment for epithelial ovarian cancer including PARP inhibitors and bevacizumab.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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留下邮箱，当我们发布与 Nicoletta Colombo（European Institute of Oncology (IEO), Milan）相关的新研究或访谈时，我们会通知你。
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