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Translational Medicine / 转化医学CEACAM5 ADC, Lung Cancer

Nicolas Isambert

MD, PhD

🏢Centre Georges-Francois Leclerc🌐France

Medical Oncologist

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👥Biography 个人简介

Dr. Nicolas Isambert is a French oncologist specializing in early-phase oncology clinical trials including novel ADC therapeutics. He has been an investigator in trials of tusamitamab ravtansine (SAR408701), an ADC targeting CEACAM5, which is overexpressed in non-squamous NSCLC. His research evaluates CEACAM5 expression as a biomarker and characterizes the efficacy and safety of maytansine-payload ADCs in lung and other solid tumors.

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🧪Research Fields 研究领域

CEACAM5 tusamitamab ravtansine
CEACAM5 expression lung cancer
non-squamous NSCLC ADC
early phase solid tumor trials
novel payload maytansine ADC

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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