Nicolas Girard
尼古拉·吉拉德
MD, PhD
Professor of Respiratory Medicine and Head of Thoracic Oncology呼吸医学教授兼胸部肿瘤学主任
👥Biography 个人简介
Nicolas Girard at Institut Curie leads France's national thymic malignancy program RYTHMIC and is a leading global authority on rare thoracic cancers. He has contributed to ITMIG staging, international thymic tumor registries, and immunotherapy trials, and coordinates the French national rare thoracic tumor network.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
RYTHMIC Network
Founded and directs RYTHMIC, the French national network for thymic malignancies, establishing multidisciplinary care pathways, a national registry, and trials infrastructure for rare thoracic tumors.
Thymic Tumor Molecular Profiling
Led comprehensive molecular characterization of thymic tumors, identifying GTF2I mutations in type A/AB thymomas and defining the molecular landscape of thymic carcinoma.
Immunotherapy in Thymic Malignancies
Conducted the NIVOTHYM trial and contributed to multiple immunotherapy studies in thymic carcinoma, while characterizing autoimmune toxicity risks specific to thymoma patients.
Representative Works 代表性著作
Nivolumab in thymic carcinoma (NIVOTHYM trial)
Journal of Thoracic Oncology (2021)
Prospective evidence for nivolumab activity in thymic carcinoma within the RYTHMIC network, informing European treatment guidelines.
GTF2I mutations in thymic epithelial tumors
Nature Genetics (2014)
Discovered recurrent GTF2I mutations as a defining molecular feature of type A and AB thymomas, elucidating a novel oncogenic pathway.
Molecular profiling of thymic malignancies: rationale and design of the RYTHMIC prospective cohort
ERJ Open Research (2017)
Established the framework for national molecular profiling of thymic tumors in France, enabling precision oncology approaches.
🏆Awards & Recognition 奖项与荣誉
📄Data Sources 数据来源
Last updated: 2026-01-15 | All information from publicly available academic sources
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