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Translational Medicine / 转化医学BRCA, PARP Inhibitors, Breast Cancer

Nicholas Turner

MD PhD

🏢The Institute of Cancer Research / Royal Marsden🌐UK

Professor

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Key Contributions

👥Biography 个人简介

Nicholas Turner at the ICR/Royal Marsden has made major contributions to understanding PARP inhibitor resistance mechanisms in BRCA-mutant breast cancer. His research on BRCA reversion mutations as a major PARP inhibitor resistance mechanism, on identifying secondary resistance pathways, and on clinical development of PARP inhibitor combinations has been influential in the breast cancer precision medicine field.

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🧪Research Fields 研究领域

PARP inhibitor resistance
BRCA reversion mutations
HRD breast cancer
talazoparib
olaparib breast cancer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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