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Translational Medicine / 转化医学Prostate Cancer, mHSPC

Nicholas James

MD, PhD

🏢The Institute of Cancer Research and Royal Marsden🌐UK

Professor of Prostate and Bladder Cancer Research

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👥Biography 个人简介

Nicholas James leads the STAMPEDE trial, the largest prostate cancer clinical trial ever conducted, which has established evidence for multiple treatment intensification strategies in mHSPC including abiraterone, docetaxel, and radiotherapy to the primary tumor. His platform trial design has efficiently evaluated numerous agents and generated practice-changing results for mHSPC. James has spearheaded collaborations between UK academic oncology networks and pharmaceutical sponsors to accelerate trial conduct. His work on STAMPEDE has influenced international treatment guidelines for mHSPC.

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🧪Research Fields 研究领域

STAMPEDE trial
mHSPC systemic therapy
abiraterone STAMPEDE
docetaxel STAMPEDE
multi-arm multi-stage trial

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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