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Translational Medicine / 转化医学Clinical Trial Innovation

Niall Tebbutt

尼尔·特布特

MBBS, PhD, FRACP

🏢Olivia Newton-John Cancer Wellness & Research Centre, Austin Health, Melbourne(奥利维亚·纽顿-约翰癌症健康与研究中心,奥斯汀健康,墨尔本)🌐Australia

Professor of Medical Oncology; Director of Clinical Research; Head, Gastrointestinal Oncology Program肿瘤内科学教授;临床研究主任;胃肠道肿瘤项目负责人

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Key Papers
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Awards
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Key Contributions

👥Biography 个人简介

Niall Tebbutt, MBBS PhD FRACP is a leading Australian GI oncologist and clinical trial innovator at the Olivia Newton-John Cancer Research Centre. He is renowned for designing and leading adaptive and biomarker-enriched trials in colorectal, gastric, and upper GI cancers, advancing precision approaches for Australasian and global patients.

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🧪Research Fields 研究领域

GI Cancer Adaptive Trials胃肠道癌症适应性试验
Colorectal Cancer Clinical Trials结直肠癌临床试验
Adaptive Trial Design适应性试验设计
Gastrointestinal Oncology胃肠道肿瘤学
Biomarker-Enriched Trial Design生物标志物富集试验设计

🎓Key Contributions 主要贡献

GI Cancer Adaptive Clinical Trials

Designed adaptive and biomarker-stratified clinical trials in colorectal and gastric cancers, advancing precision therapeutics through innovative trial methodologies within AGITG (Australasian GI Trials Group) frameworks.

Biomarker-Enriched GI Oncology Studies

Led biomarker-driven studies identifying predictive markers for anti-EGFR and anti-VEGF therapy in metastatic colorectal cancer, informing stratified treatment approaches in routine and trial settings.

Representative Works 代表性著作

[1]

Bevacizumab and Cetuximab in Colorectal Cancer: An Adaptive Biomarker Study

Journal of Clinical Oncology (2020)

Adaptive biomarker enrichment study evaluating combination biologic therapy in metastatic CRC with prospective RAS/BRAF stratification.

[2]

Predictive Biomarkers for Anti-EGFR Therapy in Metastatic Colorectal Cancer

Annals of Oncology (2018)

Comprehensive analysis of molecular predictors for anti-EGFR efficacy, informing patient selection strategies for adaptive GI cancer trials.

🏆Awards & Recognition 奖项与荣誉

🏆AGITG Clinical Trials Leadership Award
🏆Cancer Council Victoria Research Excellence Award
🏆FRACP Fellowship in Medical Oncology

📄Data Sources 数据来源

Last updated: 2026-01-15 | All information from publicly available academic sources

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