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Translational Medicine / 转化医学Neutrophil Plasticity, Pre-metastatic Niche

Neta Erez

PhD

🏢Tel Aviv University🌐Israel

Professor, Pathology

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Key Contributions

👥Biography 个人简介

Neta Erez has revealed how cancer-associated fibroblasts reprogram neutrophils to create the pre-metastatic niche, demonstrating that fibroblast-neutrophil crosstalk at distant organ sites prepares tissue for metastatic colonization before tumor cells arrive. Her work showed that tumor-conditioned neutrophils exhibit distinct transcriptional programs from steady-state neutrophils. She has contributed to understanding neutrophil plasticity in the context of organ-specific metastasis. Her research connects stromal biology with neutrophil-mediated metastatic conditioning.

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🧪Research Fields 研究领域

neutrophil plasticity cancer
pre-metastatic niche neutrophil
fibroblast neutrophil crosstalk
neutrophil bone marrow cancer
granulocyte premetastatic conditioning

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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