Neil Bhatt
MD
Associate Professor of Medical Oncology
👥Biography 个人简介
Neil Bhatt investigates mechanisms of resistance to HER2-targeted therapies in breast cancer, with emphasis on HER2 somatic mutations in previously HER2-negative tumors. His research characterized how HER2 kinase domain mutations confer sensitivity to irreversible HER2 inhibitors like neratinib. He has also studied PI3K pathway activation and HER3 upregulation as adaptive resistance mechanisms to trastuzumab. His translational work informs the use of pan-HER inhibitors in HER2-mutant metastatic breast cancer.
🧪Research Fields 研究领域
🎓Key Contributions 主要贡献
Representative Works 代表性著作
📄Data Sources 数据来源
Last updated: 2026-03-01 | All information from publicly available academic sources
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