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Translational Medicine / 转化医学Prostate Cancer Endocrine Therapy, CRPC

Neal Shore

MD FACS

🏢Carolina Urologic Research Center🌐USA

Medical Director

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Key Contributions

👥Biography 个人简介

Neal Shore has been a central investigator in clinical trials defining AR inhibitor therapy for non-metastatic and metastatic castration-resistant prostate cancer. He led the ARAMIS trial establishing darolutamide for nmCRPC and contributed to apalutamide studies. His research also characterized relugolix as an oral GnRH antagonist with cardiovascular advantages in prostate cancer. He has published extensively on hormonal therapy sequencing and resistance patterns in advanced prostate cancer.

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🧪Research Fields 研究领域

darolutamide ARAMIS
apalutamide prostate
relugolix GnRH antagonist
castration-sensitive prostate cancer
nmCRPC treatment

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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