Navdeep Chandel

Navdeep Chandel at Northwestern has contributed foundational work on mitochondrial function and reactive oxygen species (ROS) signaling in cancer. His research has demonstrated that mitochondrial ROS are not merely toxic byproducts but serve as signaling molecules that promote tumor cell survival and metastasis. He has contributed to understanding how cancer cells maintain mitochondrial function despite aerobic glycolysis and has evaluated mitochondria-targeting therapeutic strategies. His work on how antioxidant supplementation may actually promote cancer cell survival under oxidative stress has been impactful. His comprehensive mitochondrial biology contributions have advanced cancer metabolism drug discovery.