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Translational Medicine / 转化医学Avelumab, JAVELIN Merkel 200

Naseem Zojwalla

MD

🏢Merck KGaA / EMD Serono🌐USA

Vice President, Global Clinical Development

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Key Contributions

👥Biography 个人简介

Naseem Zojwalla led the global development program for avelumab (Bavencio) in Merkel cell carcinoma, which resulted in the first FDA approval of a checkpoint inhibitor for any skin cancer, initially as second-line therapy for metastatic MCC. The JAVELIN Merkel 200 trial demonstrated durable objective responses of 33% in pre-treated patients, many of which were sustained beyond two years. She oversaw the expansion of the avelumab MCC label to first-line metastatic disease and has worked on rare cancer drug development strategies for ultra-orphan indications.

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🧪Research Fields 研究领域

avelumab Bavencio MCC approval
JAVELIN Merkel 200 trial design
PD-L1 inhibitor MCC
anti-PD-L1 durable response MCC
rare cancer drug development FDA approval

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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