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Translational Medicine / 转化医学Pediatric Brain Tumors, Epigenetics

Nada Jabado

MD

🏢McGill University🌐Canada

Professor of Human Genetics and Pediatrics

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Key Contributions

👥Biography 个人简介

Nada Jabado at McGill University co-discovered the H3K27M and H3G34R/V histone mutations that characterize a large proportion of pediatric high-grade gliomas including DIPG. This landmark discovery revealed that pediatric high-grade gliomas are epigenetically distinct from adult glioblastoma, fundamentally redefining their molecular classification and identifying novel therapeutic targets in one of the deadliest pediatric brain cancers.

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🧪Research Fields 研究领域

H3K27M pediatric glioma
histone mutations cancer
DIPG
diffuse midline glioma
pediatric brain tumor epigenetics

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-02-01 | All information from publicly available academic sources

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