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Translational Medicine / 转化医学CAR-T Therapy, HER2 Targeting

Nabil Bhatt

MD, PhD

🏢Baylor College of Medicine🌐USA

Professor of Pediatric Oncology

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Key Contributions

👥Biography 个人简介

Nabil Bhatt has pioneered HER2-targeted CAR-T cell therapy for solid tumors, particularly osteosarcoma and other HER2-expressing pediatric cancers. His research has established safety profiles for HER2 CAR-T in patients who have failed standard therapies. He has developed armored CAR-T constructs that secrete cytokines to remodel the tumor microenvironment. His clinical trials have demonstrated durable responses in a subset of HER2-positive solid tumor patients.

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🧪Research Fields 研究领域

HER2 CAR-T
osteosarcoma
solid tumor cell therapy
pediatric cancer
chimeric antigen receptor

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-03-01 | All information from publicly available academic sources

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