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Translational Medicine / 转化医学HER2 Ultra-Low

Shanu Modi

MD

🏢Memorial Sloan Kettering Cancer Center🌐USA

Attending Physician, Breast Medicine Service

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Key Contributions

👥Biography 个人简介

Shanu Modi led the DESTINY-Breast04 and DESTINY-Breast06 trials that established trastuzumab deruxtecan in HER2-low and HER2-ultralow breast cancer. Her work redefined HER2 as a continuum of therapeutic targets. She continues to lead practice-changing ADC trials at MSKCC.

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🧪Research Fields 研究领域

Trastuzumab deruxtecan
DESTINY-Breast trials
HER2 biology
ADCs
Metastatic breast cancer

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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