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Translational Medicine / 转化医学CDK12 Synthetic Lethality

Paul Mischel

MD

🏢Stanford University🌐USA

Professor and Vice Chair of Research

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Key Contributions

👥Biography 个人简介

Paul Mischel is a leader in cancer cell biology with pioneering work on extrachromosomal DNA and oncogene amplification. He has extended his interests to synthetic lethal vulnerabilities including those exposed by CDK12 alterations and transcriptional dependencies in aggressive cancers. His laboratory integrates genomics, imaging, and therapeutic development.

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🧪Research Fields 研究领域

extrachromosomal DNA
glioblastoma
oncogene amplification
synthetic lethality
precision oncology

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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