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Translational Medicine / 转化医学Electrochemotherapy and Electroporation

Lluis Mir

PhD

🏢CNRS / Gustave Roussy Institute🌐France

Director of Research

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Key Contributions

👥Biography 个人简介

Lluis Mir is the inventor of electrochemotherapy, having demonstrated in 1991 that electric pulses dramatically enhance bleomycin cytotoxicity in tumors through membrane permeabilization, enabling curative treatment of previously resistant lesions. His foundational work established the principles of reversible electroporation for drug delivery and gene transfer that underpin all current clinical ECT and IRE applications. He continues to develop novel electroporation-based therapeutic modalities for cancer treatment.

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🧪Research Fields 研究领域

Electrochemotherapy invention
In vivo electroporation
Gene electrotransfer
Antitumor electrochemotherapy
Electroporation mechanisms

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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