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Translational Medicine / 转化医学Cholangiocarcinoma, Genomic Landscape

Milind Javle

MD

🏢MD Anderson Cancer Center🌐USA

Professor of Gastrointestinal Medical Oncology

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👥Biography 个人简介

Milind Javle at MD Anderson is a cholangiocarcinoma specialist who has conducted comprehensive genomic profiling studies defining the molecular landscape of intrahepatic versus extrahepatic cholangiocarcinoma. His work has characterized the prevalence of FGFR2 fusions, IDH1 mutations, KRAS, HER2, and other actionable alterations across BTC subtypes. He has been involved in early-phase trials of multiple FGFR inhibitors and has contributed to understanding the therapeutic implications of the distinct molecular profiles of iCCA versus eCCA. His comprehensive molecular profiling approach to BTC has influenced treatment guidelines.

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🧪Research Fields 研究领域

cholangiocarcinoma genomics MD Anderson
FGFR2 IDH1 BTC molecular profiling
iCCA eCCA molecular differences
biliary tract cancer sequencing
gemcitabine-cisplatin BTC backbone

🎓Key Contributions 主要贡献

Representative Works 代表性著作

📄Data Sources 数据来源

Last updated: 2026-04-01 | All information from publicly available academic sources

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